Mutation analysis of IDH1 in paired gliomas revealed IDH1 mutation was not associated with malignant progression but predicted longer survival.

Mutation analysis of IDH1 in paired gliomas revealed IDH1 mutation was not associated with malignant progression but predicted longer survival.

Recurrence and progression to higher grade lesions are characteristic behaviors of gliomas. Though IDH1 mutation frequently occurs and is considered as an early event in gliomagenesis, little is known about its role in the recurrence and progression of gliomas. We therefore analysed IDH1 and IDH2 st...

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Bibliographic Details
Main Authors: Yu Yao, Aden Ka-Yin Chan, Zhi Yong Qin, Ling Chao Chen, Xin Zhang, Jesse Chung-Sean Pang, Hiu Ming Li, Yin Wang, Ying Mao, Ho-Keung Ng, Liang Fu Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3696098?pdf=render

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http://europepmc.org/articles/PMC3696098?pdf=render

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