In vitro acetylcholinesterase inhibition by psoralen using molecular docking and enzymatic studies

Introduction: Alzheimer′s disease (AD) has increased at an alarming rate and is now a worldwide health problem. Inhibitors of acetylcholinesterase (AChE) leading to inhibition of acetylcholine breakdown constitute the main therapeutic strategy for AD. Psoralen was investigated as inhibitor of AChE e...

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Bibliographic Details
Main Authors: Gauresh Somani, Chinmay Kulkarni, Prashant Shinde, Rupesh Shelke, Kirti Laddha, Sadhana Sathaye
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=1;spage=32;epage=36;aulast=Somani