cAMP-PKA dependent ERK1/2 activation is necessary for vanillic acid potentiated glucose-stimulated insulin secretion in pancreatic β-cells

Vanillic acid (VA), a dietary phenolic compound is generally studied for its anti-oxidative and anti-inflammatory effects. However, the effect of VA on insulin secretion and its mechanism of action has never been explored. In this study, we report that VA augments glucose-stimulated insulin secretio...

Full description

Bibliographic Details
Main Authors: V.P. Mahendra, Devendra J. Haware, Ravi Kumar
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Journal of Functional Foods
Subjects:
PKA
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619301197