Evaluation of a connectivity-based imaging metric that reflects functional decline in Multiple Sclerosis.

Cognitive impairment is a common symptom in individuals with Multiple Sclerosis (MS), but meaningful, reliable biomarkers relating to cognitive decline have been elusive, making evaluation of the impact of therapeutics on cognitive function difficult. Here, we combine pathway-based MRI measures of s...

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Bibliographic Details
Main Authors: Katherine A Koenig, Erik B Beall, Ken E Sakaie, Daniel Ontaneda, Lael Stone, Stephen M Rao, Kunio Nakamura, Stephen E Jones, Mark J Lowe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0251338