The normal chain length distribution of the O antigen is required for the interaction of Shigella flexneri 2a with polarized Caco-2 cells

Shigella flexneri causes bacillary dysentery in humans. Essential to the establishment of the disease is the invasion of the colonic epithelial cells. Here we investigated the role of the lipopolysaccharide (LPS) O antigen in the ability of S. flexneri to adhere to and invade polarized Caco-2 cells....

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Bibliographic Details
Main Authors: Anilei Hoare, Denisse Bravo, Mara Martinic, Miguel A Valvano, Inés Contreras, Sergio A Álvarez
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000100003