Pivotal Role for Cxcr2 in Regulating Tumor-Associated Neutrophil in Breast Cancer

Pivotal Role for Cxcr2 in Regulating Tumor-Associated Neutrophil in Breast Cancer

Chemokines present in the tumor microenvironment are essential for the control of tumor progression. We show here that several ligands of the chemokine receptor Cxcr2 were up-regulated in the PyMT (polyoma middle T oncogene) model of breast cancer. Interestingly, the knock-down of Cxcr2 in PyMT anim...

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Bibliographic Details
Main Authors: Colin Timaxian, Christoph F. A. Vogel, Charlotte Orcel, Diana Vetter, Camille Durochat, Clarisse Chinal, Phuong NGuyen, Marie-Laure Aknin, Françoise Mercier-Nomé, Martin Davy, Isabelle Raymond-Letron, Thi-Nhu-Ngoc Van, Sarah D. Diermeier, Anastasia Godefroy, Magali Gary-Bobo, Franck Molina, Karl Balabanian, Gwendal Lazennec
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
chemokine receptors
breast cancer
Cxcr2
neutrophils
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/13/11/2584

Internet

https://www.mdpi.com/2072-6694/13/11/2584

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