Host age and expression of genes involved in red blood cell invasion in Plasmodium falciparum field isolates

Host age and expression of genes involved in red blood cell invasion in Plasmodium falciparum field isolates

Abstract Plasmodium falciparum proteins involved in erythrocyte invasion are main targets of acquired immunity and important vaccine candidates. We hypothesized that anti-parasite immunity acquired upon exposure would limit invasion-related gene (IRG) expression and affect the clinical impact of the...

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Bibliographic Details
Main Authors: Aida Valmaseda, Quique Bassat, Pedro Aide, Pau Cisteró, Alfons Jiménez, Aina Casellas, Sonia Machevo, Ruth Aguilar, Betuel Sigaúque, Virander S. Chauhan, Christine Langer, James Beeson, Chetan Chitnis, Pedro L. Alonso, Deepak Gaur, Alfredo Mayor
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05025-5

Internet

https://doi.org/10.1038/s41598-017-05025-5

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