Exploring the role of RRM domains and conserved aromatic residues in RGG motif  of eIF4G-binding translation repressor protein Sbp1 [version 3; peer review: 3 approved, 1 approved with reservations]

Background: RNA binding proteins play crucial role in determining if a given mRNA will be translated, stored, or degraded. Sbp1 is an RGG-motif containing protein that is implicated in affecting mRNA decapping and translation. Sbp1 represses translation by binding eIF4G1 through its RGG-motif and ac...

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Bibliographic Details
Main Authors: Nupur Bhatter, Rajan Iyyappan, Gayatri Mohanan, Purusharth I Rajyaguru
Format: Article
Language:English
Published: Wellcome 2021-09-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-102/v3