Exploring the role of RRM domains and conserved aromatic residues in RGG motif of eIF4G-binding translation repressor protein Sbp1 [version 3; peer review: 3 approved, 1 approved with reservations]
Background: RNA binding proteins play crucial role in determining if a given mRNA will be translated, stored, or degraded. Sbp1 is an RGG-motif containing protein that is implicated in affecting mRNA decapping and translation. Sbp1 represses translation by binding eIF4G1 through its RGG-motif and ac...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wellcome
2021-09-01
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Series: | Wellcome Open Research |
Online Access: | https://wellcomeopenresearch.org/articles/3-102/v3 |