Circulating T cell-monocyte complexes are markers of immune perturbations

Circulating T cell-monocyte complexes are markers of immune perturbations

Our results highlight for the first time that a significant proportion of cell doublets in flow cytometry, previously believed to be the result of technical artifacts and thus ignored in data acquisition and analysis, are the result of biological interaction between immune cells. In particular, we s...

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Bibliographic Details
Main Authors: Julie G Burel, Mikhail Pomaznoy, Cecilia S Lindestam Arlehamn, Daniela Weiskopf, Ricardo da Silva Antunes, Yunmin Jung, Mariana Babor, Veronique Schulten, Gregory Seumois, Jason A Greenbaum, Sunil Premawansa, Gayani Premawansa, Ananda Wijewickrama, Dhammika Vidanagama, Bandu Gunasena, Rashmi Tippalagama, Aruna D deSilva, Robert H Gilman, Mayuko Saito, Randy Taplitz, Klaus Ley, Pandurangan Vijayanand, Alessandro Sette, Bjoern Peters
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-06-01
Series:eLife
Subjects:
flow cytometry
immune biomarker
infectious diseases
cell interactions
Online Access:https://elifesciences.org/articles/46045

Internet

https://elifesciences.org/articles/46045

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