mtDNA Heteroplasmy: Origin, Detection, Significance, and Evolutionary Consequences

Mitochondrial DNA (mtDNA) is predominately uniparentally transmitted. This results in organisms with a single type of mtDNA (homoplasmy), but two or more mtDNA haplotypes have been observed in low frequency in several species (heteroplasmy). In this review, we aim to highlight several aspects of het...

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Bibliographic Details
Main Authors: Maria-Eleni Parakatselaki, Emmanuel D. Ladoukakis
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/7/633