Therapeutic efficacy of α-radioimmunotherapy with different activity levels of the 213Bi-labeled monoclonal antibody MX35 in an ovarian cancer model

Therapeutic efficacy of α-radioimmunotherapy with different activity levels of the 213Bi-labeled monoclonal antibody MX35 in an ovarian cancer model

Abstract Background The aim of this study was to compare the therapeutic efficacy of two different activity levels of the 213Bi-labeled monoclonal antibody MX35 in an ovarian cancer model. Sixty female BALB/c (nu/nu) mice were inoculated intraperitoneally with human ovarian cancer cells (OVCAR-3). T...

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Bibliographic Details
Main Authors: Anna Gustafsson-Lutz, Tom Bäck, Emma Aneheim, Ragnar Hultborn, Stig Palm, Lars Jacobsson, Alfred Morgenstern, Frank Bruchertseifer, Per Albertsson, Sture Lindegren
Format: Article
Language:English
Published: SpringerOpen 2017-04-01
Series:EJNMMI Research
Subjects:
Radioimmunotherapy
Dosimetry
High LET radiation
Monoclonal antibodies (mAb)
Radiopharmaceuticals
Online Access:http://link.springer.com/article/10.1186/s13550-017-0283-2

Internet

http://link.springer.com/article/10.1186/s13550-017-0283-2

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