Exacerbation of autoimmune neuro-inflammation in mice cured from blood-stage Plasmodium berghei infection.

Exacerbation of autoimmune neuro-inflammation in mice cured from blood-stage Plasmodium berghei infection.

The thymus plays an important role shaping the T cell repertoire in the periphery, partly, through the elimination of inflammatory auto-reactive cells. It has been shown that, during Plasmodium berghei infection, the thymus is rendered atrophic by the premature egress of CD4+CD8+ double-positive (DP...

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Main Authors: Rodolfo Thomé, André Luis Bombeiro, Luidy Kazuo Issayama, Catarina Rapôso, Stefanie Costa Pinto Lopes, Thiago Alves da Costa, Rosária Di Gangi, Isadora Tassinari Ferreira, Ana Leda Figueiredo Longhini, Alexandre Leite Rodrigues Oliveira, Maria Alice da Cruz Höfling, Fábio Trindade Maranhão Costa, Liana Verinaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4201583?pdf=render

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http://europepmc.org/articles/PMC4201583?pdf=render

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