Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid

Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid

The Lactobacillus-dominated vaginal microbiota is associated with a reduced risk of acquiring and transmitting HIV and other sexually transmitted infections (STIs). Lactic acid is a major organic acid metabolite produced by lactobacilli that acidifies the vagina and has been reported to have inhibit...

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Bibliographic Details
Main Authors: David Tyssen, Ying-Ying Wang, Joshua A. Hayward, Paul A. Agius, Kevin DeLong, Muriel Aldunate, Jacques Ravel, Thomas R. Moench, Richard A. Cone, Gilda Tachedjian
Format: Article
Language:English
Published: American Society for Microbiology 2018-07-01
Series:mSphere
Subjects:
HIV transmission
Lactobacillus
human immunodeficiency virus
metabolite
microbiota
vagina
Online Access:https://doi.org/10.1128/mSphere.00055-18

Internet

https://doi.org/10.1128/mSphere.00055-18

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