Expression of tumor growth related genes in IRE1 knockdown U87 glioma cells: effect of hypoxia

We have studied the effect of IRE1 signaling enzyme knockdown as well as hypoxia on the expression of genes encoding the important tumor growth related proteins (BRCA1, DEK, BCL2L1, COL6A1, TPD52, HOMER3, and GNPDA1) in U87 glioma cells. It was shown that the expression level of breast cancer 1 earl...

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Bibliographic Details
Main Authors: O. H. Minchenko, O. Y. Luzina, O. S. Hnatiuk, D. O. Minchenko, I. A. Garmash, O. O. Ratushna
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2017-10-01
Series:Ukrainian Biochemical Journal
Subjects:
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2017/10/Minchenko_5-17.pdf