Hyperpolarized Amino Acid Derivatives as Multivalent Magnetic Resonance pH Sensor Molecules

Hyperpolarized Amino Acid Derivatives as Multivalent Magnetic Resonance pH Sensor Molecules

pH is a tightly regulated physiological parameter that is often altered in diseased states like cancer. The development of biosensors that can be used to non-invasively image pH with hyperpolarized (HP) magnetic resonance spectroscopic imaging has therefore recently gained tremendous interest. Howev...

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Bibliographic Details
Main Authors: Christian Hundshammer, Stephan Düwel, David Ruseckas, Geoffrey Topping, Piotr Dzien, Christoph Müller, Benedikt Feuerecker, Jan B. Hövener, Axel Haase, Markus Schwaiger, Steffen J. Glaser, Franz Schilling
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Sensors
Subjects:
pH sensors
hyperpolarized
dissolution dynamic nuclear polarization
magnetic resonance spectroscopic imaging
nuclear magnetic resonance
amino acids
Online Access:http://www.mdpi.com/1424-8220/18/2/600

Internet

http://www.mdpi.com/1424-8220/18/2/600

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