Biomarkers of TGF-β signaling pathway and prognosis of pancreatic cancer.

Transforming growth factor (TGF)-β signaling pathway, may act both as a tumor suppressor and as a tumor promoter in pancreatic cancer, depending on tumor stage and cellular context. TGF-β pathway has been under intensive investigation as a potential therapeutic target in the treatment of cancer. We...

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Bibliographic Details
Main Authors: Milind Javle, Yanan Li, Dongfeng Tan, Xiaoqun Dong, Ping Chang, Siddhartha Kar, Donghui Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3896410?pdf=render