Accelerated vascular aging in CuZnSOD-deficient mice: impact on EPC function and reparative neovascularization.

Aging is associated with increased oxidative stress levels and impaired neovascularization following ischemia. CuZnSOD has an important role to limit oxidative stress in the vasculature. Here we investigated the role of CuZnSOD for the modulation of ischemia-induced neovascularisation during aging.H...

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Bibliographic Details
Main Authors: Jessika Groleau, Sylvie Dussault, Julie Turgeon, Paola Haddad, Alain Rivard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3155535?pdf=render