CD80 expression is upregulated by TP53 activation in human cancer epithelial cells

CD80 is recognized as one of the most potent costimulatory molecules by which immune cells limit cancer progression; however, the current understanding of the regulation of its expression on human tumor cells is limited. The TP53 tumor suppressor plays a critical role in cancer and its significant r...

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Bibliographic Details
Main Authors: Melania Scarpa, Chiara Marchiori, Marco Scarpa, Ignazio Castagliuolo
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1907912