A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use
Abstract Background It has become increasingly apparent that the trophectoderm (TE) at blastocyst stage is much more mosaic than has been appreciated. Whether preimplantation genetic screening (PGS), utilizing a single TE biopsy (TEB), can reliably determine embryo ploidy has, therefore, increasingl...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-04-01
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Series: | Reproductive Biology and Endocrinology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12958-017-0251-8 |