Microscopic Isthmuses and Fibrosis Within the Border Zone of Infarcted Hearts Promote Calcium-Mediated Ectopy and Conduction Block

Microscopic Isthmuses and Fibrosis Within the Border Zone of Infarcted Hearts Promote Calcium-Mediated Ectopy and Conduction Block

Ventricular tachycardia (VT) secondary to myocardial infarction (MI) remain a major cause of sudden death in adults. Premature ventricular complexes (PVCs), the first initiating beats of a portion of these arrhythmias, arise from triggered activity in the infarct border zone (BZ). At the cellular sc...

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Bibliographic Details
Main Authors: Fernando O. Campos, Yohannes Shiferaw, Rodrigo Weber dos Santos, Gernot Plank, Martin J. Bishop
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Physics
Subjects:
myocardial infarction
isthmus
fibrosis
arrhythmia
triggered activity
calcium
Online Access:https://www.frontiersin.org/article/10.3389/fphy.2018.00057/full

Internet

https://www.frontiersin.org/article/10.3389/fphy.2018.00057/full

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