Influence of the rs1080985 Single Nucleotide Polymorphism of the CYP2D6 Gene and APOE Polymorphism on the Response to Donepezil Treatment in Patients with Alzheimer's Disease in China

Background/Aim: Recent data have indicated that the rs1080985 single nucleotide polymorphism (SNP) of the cytochrome P450 (CYP) 2D6 and the common apolipoprotein E (APOE) gene may affect the response to donepezil in patients with Alzheimer's disease (AD). We investigated this association in Chi...

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Bibliographic Details
Main Authors: Mengyuan Liu, Ying Zhang, Ya Ruth Huo, Shuling Liu, Shuai Liu, Junwei Wang, Change Wang, Jinhuan Wang, Yong Ji
Format: Article
Language:English
Published: Karger Publishers 2014-11-01
Series:Dementia and Geriatric Cognitive Disorders Extra
Subjects:
Online Access:http://www.karger.com/Article/FullText/367596