Apolipoprotein E-C1-C4-C2 gene cluster region and inter-individual variation in plasma lipoprotein levels: a comprehensive genetic association study in two ethnic groups.

The apolipoprotein E-C1-C4-C2 gene cluster at 19q13.32 encodes four amphipathic apolipoproteins. The influence of APOE common polymorphisms on plasma lipid/lipoprotein profile, especially on LDL-related traits, is well recognized; however, little is known about the role of other genes/variants in th...

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Main Authors: Dilek Pirim, Zaheda H Radwan, Xingbin Wang, Vipavee Niemsiri, John E Hokanson, Richard F Hamman, Eleanor Feingold, Clareann H Bunker, F Yesim Demirci, M Ilyas Kamboh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214060