Ligand-protein interactions of plant-isolated (9z,12z)-octadeca-9,12-dienoic acid with Β-ketoacyl-Acp synthase (KasA) in potential anti-tubercular drug designing

Ligand-protein interactions of plant-isolated (9z,12z)-octadeca-9,12-dienoic acid with Β-ketoacyl-Acp synthase (KasA) in potential anti-tubercular drug designing

Mycobacterium tuberculosis remains one of the world's contributors to mortality. With the emergence of SARS-CoV-2 coinfections, patients with TB are predisposed to being more heavily weighed down by COVID-19 disease and its opportunistic coinfections. The severity of the disease coupled with dr...

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Bibliographic Details
Main Authors: Andrew G. Mtewa, Jonathan T. Bvunzawabaya, Kennedy J. Ngwira, Fanuel Lampiao, Reuben Maghembe, Hedmon Okella, Anke weisheit, Casim U. Tolo, Patrick E. Ogwang, Duncan C. Sesaazi
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Scientific African
Subjects:
Ligand efficiency
β-ketoacyl-ACP synthase
Drug design
KasA inhibitor
Drug-protein interactions
M. tuberculosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227621001289

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http://www.sciencedirect.com/science/article/pii/S2468227621001289

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