Structure of the HLA-DR-DQ-genotype in children with coeliac disease

Structure of the HLA-DR-DQ-genotype in children with coeliac disease

Introduction. Coeliac disease is a genetically determined disease associated with the HLA-DQ2 and DQ8 genes. According to European data, these alleles are detected in more than 95% of patients. The results of earlier studies in various regions of the Russian Federation and the constituent republics...

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Bibliographic Details
Main Authors: Yu. A. Dmitrieva, E. A. Roslavtseva, V. A. Kuryaninova, I. N. Zakharova, T. E. Borovik, E. N. Kasatkina, L. Ya. Klimov, A. V. Ivanova, E. R. Radchenko, O. V. Shuleshko
Format: Article
Language:Russian
Published: Remedium Group LLC 2020-07-01
Series:Медицинский совет
Subjects:
coeliac disease
children
main histocompatibility complex
hla-dr-dq haplotype
hla-dq2/dq8
gene-dosage effect
genetic risk
Online Access:https://www.med-sovet.pro/jour/article/view/5723

Internet

https://www.med-sovet.pro/jour/article/view/5723

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