Gestational chronodisruption impairs hippocampal expression of NMDA receptor subunits Grin1b/Grin3a and spatial memory in the adult offspring.

Epidemiological and experimental evidence correlates adverse intrauterine conditions with the onset of disease later in life. For a fetus to achieve a successful transition to extrauterine life, a myriad of temporally integrated humoral/biophysical signals must be accurately provided by the mother....

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Bibliographic Details
Main Authors: Nelson Vilches, Carlos Spichiger, Natalia Mendez, Lorena Abarzua-Catalan, Hugo A Galdames, David G Hazlerigg, Hans G Richter, Claudia Torres-Farfan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3963867?pdf=render