The effects of O-GlcNAc alteration on Alzheimer-like neurodegeneration in SK-N-SH cells

Background: O-GlcNAcylation is a highly dynamic post-translational modification that plays a key role in regulating phosphorylation of protein and cell survival. The proteins O-GlcNAcylation level is regulated dynamically by O-GlcNAc transferase (OGT) and β-N-acetylglucosaminidase (O-GlcNAcase, OGA...

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Bibliographic Details
Main Authors: Nan Ding, Peng Peng, Yu-Jing Chu, Jing-Jing Wang, Shu-Yi Chen, Renuka Arulthas, Yan-Qiu Deng
Format: Article
Language:English
Published: Palacký University Olomouc, Faculty of Medicine and Dentistry 2018-09-01
Series:Biomedical Papers
Subjects:
Online Access:https://biomed.papers.upol.cz/artkey/bio-201803-0013_the_effects_of_o-glcnac_alteration_on_alzheimer-like_neurodegeneration_in_sk-n-sh_cells.php