Cellular and molecular bases of the initiation of fever.

Cellular and molecular bases of the initiation of fever.

All phases of lipopolysaccharide (LPS)-induced fever are mediated by prostaglandin (PG) E2. It is known that the second febrile phase (which starts at approximately 1.5 h post-LPS) and subsequent phases are mediated by PGE2 that originated in endotheliocytes and perivascular cells of the brain. Howe...

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Bibliographic Details
Main Authors: Alexandre A Steiner, Andrei I Ivanov, Jordi Serrats, Hiroshi Hosokawa, Allison N Phayre, Jared R Robbins, Jennifer L Roberts, Shigeo Kobayashi, Kiyoshi Matsumura, Paul E Sawchenko, Andrej A Romanovsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1551923?pdf=render

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http://europepmc.org/articles/PMC1551923?pdf=render

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