Nitric oxide debilitates the neuropathogenic schistosome Trichobilharzia regenti in mice, partly by inhibiting its vital peptidases

Nitric oxide debilitates the neuropathogenic schistosome Trichobilharzia regenti in mice, partly by inhibiting its vital peptidases

Abstract Background Avian schistosomes, the causative agents of human cercarial dermatitis (or swimmer’s itch), die in mammals but the mechanisms responsible for parasite elimination are unknown. Here we examined the role of reactive nitrogen species, nitric oxide (NO) and peroxynitrite, in the immu...

Full description

Bibliographic Details
Main Authors: Tomáš Macháček, Barbora Šmídová, Jan Pankrác, Martin Majer, Jana Bulantová, Petr Horák
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Parasites & Vectors
Subjects:
Nitric oxide
Nitric oxide synthase
3-Nitrotyrosine
Peroxynitrite
Cathepsin B
Schistosomatidae
Online Access:http://link.springer.com/article/10.1186/s13071-020-04279-9

Internet

http://link.springer.com/article/10.1186/s13071-020-04279-9

Similar Items