Role of JNK and ERK1/2 MAPK signaling pathway in testicular injury of rats induced by di-N-butyl-phthalate (DBP)

Abstract Background Di-N-butyl-phthalate (DBP) is an endocrine disrupting substance. We investigated the adverse effect of DBP on testis of male rat and reveal its potential mechanism of MAPK signaling pathway involved this effect in vivo and in vitro. Gonadal hormone, sperm quality, morphological c...

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Bibliographic Details
Main Authors: Hongyan Wang, Weipeng Zhou, Jing Zhang, Huan Li
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Biological Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40659-019-0248-1