A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin
Robust biomarkers of aging have been developed from DNA methylation in humans and more recently, in mice. This study aimed to generate a novel epigenetic clock in rats—a model with unique physical, physiological, and biochemical advantages—by incorporating behavioral data, unsupervised machine learn...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/59201 |