Nasal DNA methylation differentiates corticosteroid treatment response in pediatric asthma: A pilot study.

Nasal DNA methylation differentiates corticosteroid treatment response in pediatric asthma: A pilot study.

BACKGROUND:Treatment response to systemic corticosteroid in asthmatic children is heterogeneous and may be mediated by epigenetic mechanism(s). We aim to identify DNA methylation (DNAm) changes responsive to steroid, and DNAm biomarkers that distinguish treatment response. MATERIALS AND METHODS:We f...

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Bibliographic Details
Main Authors: Xue Zhang, Jocelyn M Biagini Myers, Veda K Yadagiri, Ashley Ulm, Xiaoting Chen, Matthew T Weirauch, Gurjit K Khurana Hershey, Hong Ji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5640236?pdf=render

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http://europepmc.org/articles/PMC5640236?pdf=render

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