Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures
Innate immunity mediated by microglia appears to play a crucial role in initiating and propagating seizure-induced inflammatory responses. To address the role of activated microglia in the pathogenesis of childhood epilepsy, we first examined the time course of microglia activation following kainic...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-05-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996112000484 |