SFRP1 reduction results in an increased sensitivity to TGF-β signaling

<p>Abstract</p> <p>Background</p> <p>Transforming growth factor (TGF)-β plays a dual role during mammary gland development and tumorigenesis and has been shown to stimulate epithelial-mesenchymal transition (EMT) as well as cellular migration. The Wnt/β-catenin pathway...

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Bibliographic Details
Main Authors: Murray Molly E, Chenausky Kerry L, Gauger Kelly J, Schneider Sallie S
Format: Article
Language:English
Published: BMC 2011-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/59