Discovery of Functional Alternatively Spliced <i>PKM</i> Transcripts in Human Cancers

Discovery of Functional Alternatively Spliced <i>PKM</i> Transcripts in Human Cancers

Pyruvate kinase muscle type (<i>PKM</i>) is a key enzyme in glycolysis and plays an important oncological role in cancer. However, the association of <i>PKM</i> expression and the survival outcome of patients with different cancers is controversial. We employed systems biolog...

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Bibliographic Details
Main Authors: Xiangyu Li, Woonghee Kim, Muhammad Arif, Chunxia Gao, Andreas Hober, David Kotol, Linnéa Strandberg, Björn Forsström, Åsa Sivertsson, Per Oksvold, Hasan Turkez, Morten Grøtli, Yusuke Sato, Haruki Kume, Seishi Ogawa, Jan Boren, Jens Nielsen, Mathias Uhlen, Cheng Zhang, Adil Mardinoglu
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
alternative splicing
cancer
<i>PKM</i>
transcriptomics
Online Access:https://www.mdpi.com/2072-6694/13/2/348

Internet

https://www.mdpi.com/2072-6694/13/2/348

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