Evaluation of the in vivo genotoxicity of liposomal formulation for delivering anticancer estrogenic derivative (ESC8) in a mouse model

The genotoxic potential of glucocorticoid receptor (GR)-targeted liposomal formulations of the anticancer drug molecule ESC8 was studied in vivo. A methodical literature review discovered no previous studies on the genotoxicity of ESC8. Genotoxicity was assessed in both male and female mice by vario...

Full description

Bibliographic Details
Main Authors: Ajaz Ahmad, Basit Latief Jan, Mohammad Raish, Hari Krishna Reddy Rachamalla, Rajkumar Banerjee, Debabrata Mukhopadhyay, Khalid M. Alkharfy
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S131901641930043X