CYP2C19*2 and prognosis after an acute coronary syndrome: Insights from a Portuguese center

CYP2C19*2 and prognosis after an acute coronary syndrome: Insights from a Portuguese center

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Background: Clopidogrel requires oxidation dependent on the cytochrome P450 enzyme 2C19 (CYP2C19) to form its active metabolite. The importance of loss-of-function alleles (particularly CYP2C19*2, 681G>A) in poor platelet response to clopidogrel is well recognized. Objective: To investigate the p...

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Bibliographic Details
Main Authors: Rogério Teixeira, Pedro Monteiro, Gilberto Marques, João Pego, Margarida Lourenço, Carlos Tavares, Alda Reboredo, Sílvia Monteiro, Francisco Gonçalves, Maria J. Ferreira, Mário Freitas, Graça Ribeiro, Luís A. Providência
Format: Article
Language:English
Published: Elsevier 2012-04-01
Series:Revista Portuguesa de Cardiologia (English Edition)
Online Access:http://www.sciencedirect.com/science/article/pii/S2174204912000542

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http://www.sciencedirect.com/science/article/pii/S2174204912000542

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