CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature
CIC-rearranged round cell sarcoma (CRS) is a rare entity that presents in various anatomical locations and involves deep soft-tissue structures and skin. Although commonly confused with and clinically similar to Ewing sarcoma (ES), investigators have recently shown that this unique condition maintai...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-08-01
|
Series: | Gynecologic Oncology Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352578920300588 |
id |
doaj-9e08b2d2a3e34a1597979987b3225e02 |
---|---|
record_format |
Article |
spelling |
doaj-9e08b2d2a3e34a1597979987b3225e022020-11-25T03:40:50ZengElsevierGynecologic Oncology Reports2352-57892020-08-0133100592CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literatureShaina Sedighim0Jonathan Burke1Douglas Schneider2Talia Kamdjou3Julio A. Diaz-Perez4Jonathan Trent5Mecker Möller6University of Miami, Miller School of Medicine, Miami, FL, United States; Corresponding author at: University of Miami, Miller School of Medicine, 1600 NW 10th Ave, Miami, FL 33136, United States.University of Miami, Miller School of Medicine, Miami, FL, United StatesUniversity of California, Irvine School of Medicine, Orange, CA, United StatesSackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelUniversity of Miami, Miller School of Medicine Department of Pathology, Miami, FL, United StatesUniversity of Miami, Miller School of Medicine Department of Hematology and Oncology, Miami, FL, United StatesUniversity of Miami, Miller School of Medicine, Miami, FL, United States; University of Miami, Miller School of Medicine Department Surgery, Division of Surgical Oncology, Miami, FL, United StatesCIC-rearranged round cell sarcoma (CRS) is a rare entity that presents in various anatomical locations and involves deep soft-tissue structures and skin. Although commonly confused with and clinically similar to Ewing sarcoma (ES), investigators have recently shown that this unique condition maintains morphologic and pathologic features that are distinct from ES. In this report, we present and discuss a case of CRS of the uterus, the first of its kind to be reported in the English-language literature. We urge the scientific community to continue its investigations in elucidating the features of this entity, as young women who suffer from this condition have dismal prognoses and currently do not have access to therapeutic options for cure.http://www.sciencedirect.com/science/article/pii/S2352578920300588CIC-rearranged round cell sarcomaEwing sarcomaUterine sarcomaUterine cancerEwing-like sarcoma |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Shaina Sedighim Jonathan Burke Douglas Schneider Talia Kamdjou Julio A. Diaz-Perez Jonathan Trent Mecker Möller |
spellingShingle |
Shaina Sedighim Jonathan Burke Douglas Schneider Talia Kamdjou Julio A. Diaz-Perez Jonathan Trent Mecker Möller CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature Gynecologic Oncology Reports CIC-rearranged round cell sarcoma Ewing sarcoma Uterine sarcoma Uterine cancer Ewing-like sarcoma |
author_facet |
Shaina Sedighim Jonathan Burke Douglas Schneider Talia Kamdjou Julio A. Diaz-Perez Jonathan Trent Mecker Möller |
author_sort |
Shaina Sedighim |
title |
CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature |
title_short |
CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature |
title_full |
CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature |
title_fullStr |
CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature |
title_full_unstemmed |
CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature |
title_sort |
cic-rearranged round cell (ewing-like) sarcoma of the uterus: review of the literature |
publisher |
Elsevier |
series |
Gynecologic Oncology Reports |
issn |
2352-5789 |
publishDate |
2020-08-01 |
description |
CIC-rearranged round cell sarcoma (CRS) is a rare entity that presents in various anatomical locations and involves deep soft-tissue structures and skin. Although commonly confused with and clinically similar to Ewing sarcoma (ES), investigators have recently shown that this unique condition maintains morphologic and pathologic features that are distinct from ES. In this report, we present and discuss a case of CRS of the uterus, the first of its kind to be reported in the English-language literature. We urge the scientific community to continue its investigations in elucidating the features of this entity, as young women who suffer from this condition have dismal prognoses and currently do not have access to therapeutic options for cure. |
topic |
CIC-rearranged round cell sarcoma Ewing sarcoma Uterine sarcoma Uterine cancer Ewing-like sarcoma |
url |
http://www.sciencedirect.com/science/article/pii/S2352578920300588 |
work_keys_str_mv |
AT shainasedighim cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature AT jonathanburke cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature AT douglasschneider cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature AT taliakamdjou cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature AT julioadiazperez cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature AT jonathantrent cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature AT meckermoller cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature |
_version_ |
1724532611081043968 |