CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature

CIC-rearranged round cell sarcoma (CRS) is a rare entity that presents in various anatomical locations and involves deep soft-tissue structures and skin. Although commonly confused with and clinically similar to Ewing sarcoma (ES), investigators have recently shown that this unique condition maintai...

Full description

Bibliographic Details
Main Authors: Shaina Sedighim, Jonathan Burke, Douglas Schneider, Talia Kamdjou, Julio A. Diaz-Perez, Jonathan Trent, Mecker Möller
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Gynecologic Oncology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578920300588
id doaj-9e08b2d2a3e34a1597979987b3225e02
record_format Article
spelling doaj-9e08b2d2a3e34a1597979987b3225e022020-11-25T03:40:50ZengElsevierGynecologic Oncology Reports2352-57892020-08-0133100592CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literatureShaina Sedighim0Jonathan Burke1Douglas Schneider2Talia Kamdjou3Julio A. Diaz-Perez4Jonathan Trent5Mecker Möller6University of Miami, Miller School of Medicine, Miami, FL, United States; Corresponding author at: University of Miami, Miller School of Medicine, 1600 NW 10th Ave, Miami, FL 33136, United States.University of Miami, Miller School of Medicine, Miami, FL, United StatesUniversity of California, Irvine School of Medicine, Orange, CA, United StatesSackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelUniversity of Miami, Miller School of Medicine Department of Pathology, Miami, FL, United StatesUniversity of Miami, Miller School of Medicine Department of Hematology and Oncology, Miami, FL, United StatesUniversity of Miami, Miller School of Medicine, Miami, FL, United States; University of Miami, Miller School of Medicine Department Surgery, Division of Surgical Oncology, Miami, FL, United StatesCIC-rearranged round cell sarcoma (CRS) is a rare entity that presents in various anatomical locations and involves deep soft-tissue structures and skin. Although commonly confused with and clinically similar to Ewing sarcoma (ES), investigators have recently shown that this unique condition maintains morphologic and pathologic features that are distinct from ES. In this report, we present and discuss a case of CRS of the uterus, the first of its kind to be reported in the English-language literature. We urge the scientific community to continue its investigations in elucidating the features of this entity, as young women who suffer from this condition have dismal prognoses and currently do not have access to therapeutic options for cure.http://www.sciencedirect.com/science/article/pii/S2352578920300588CIC-rearranged round cell sarcomaEwing sarcomaUterine sarcomaUterine cancerEwing-like sarcoma
collection DOAJ
language English
format Article
sources DOAJ
author Shaina Sedighim
Jonathan Burke
Douglas Schneider
Talia Kamdjou
Julio A. Diaz-Perez
Jonathan Trent
Mecker Möller
spellingShingle Shaina Sedighim
Jonathan Burke
Douglas Schneider
Talia Kamdjou
Julio A. Diaz-Perez
Jonathan Trent
Mecker Möller
CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature
Gynecologic Oncology Reports
CIC-rearranged round cell sarcoma
Ewing sarcoma
Uterine sarcoma
Uterine cancer
Ewing-like sarcoma
author_facet Shaina Sedighim
Jonathan Burke
Douglas Schneider
Talia Kamdjou
Julio A. Diaz-Perez
Jonathan Trent
Mecker Möller
author_sort Shaina Sedighim
title CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature
title_short CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature
title_full CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature
title_fullStr CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature
title_full_unstemmed CIC-rearranged round cell (Ewing-like) sarcoma of the uterus: Review of the literature
title_sort cic-rearranged round cell (ewing-like) sarcoma of the uterus: review of the literature
publisher Elsevier
series Gynecologic Oncology Reports
issn 2352-5789
publishDate 2020-08-01
description CIC-rearranged round cell sarcoma (CRS) is a rare entity that presents in various anatomical locations and involves deep soft-tissue structures and skin. Although commonly confused with and clinically similar to Ewing sarcoma (ES), investigators have recently shown that this unique condition maintains morphologic and pathologic features that are distinct from ES. In this report, we present and discuss a case of CRS of the uterus, the first of its kind to be reported in the English-language literature. We urge the scientific community to continue its investigations in elucidating the features of this entity, as young women who suffer from this condition have dismal prognoses and currently do not have access to therapeutic options for cure.
topic CIC-rearranged round cell sarcoma
Ewing sarcoma
Uterine sarcoma
Uterine cancer
Ewing-like sarcoma
url http://www.sciencedirect.com/science/article/pii/S2352578920300588
work_keys_str_mv AT shainasedighim cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature
AT jonathanburke cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature
AT douglasschneider cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature
AT taliakamdjou cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature
AT julioadiazperez cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature
AT jonathantrent cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature
AT meckermoller cicrearrangedroundcellewinglikesarcomaoftheuterusreviewoftheliterature
_version_ 1724532611081043968