Regulation of podosome formation, microglial migration and invasion by Ca<sup>2+</sup>-signaling molecules expressed in podosomes

Regulation of podosome formation, microglial migration and invasion by Ca<sup>2+</sup>-signaling molecules expressed in podosomes

<p>Abstract</p> <p>Background</p> <p>Microglia migrate during brain development and after CNS injury, but it is not known how they degrade the extracellular matrix (ECM) to accomplish this. Podosomes are tiny structures with the unique ability to adhere to and dissolve...

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Bibliographic Details
Main Authors: Siddiqui Tamjeed A, Lively Starlee, Vincent Catherine, Schlichter Lyanne C
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Journal of Neuroinflammation
Subjects:
Small-conductance Ca<sup>2+</sup>-activated K<sup>+</sup> channel
Ca<sup>2+</sup>-binding molecules
Calmodulin
Cell adhesion
Cell migration and invasion
Extracellular matrix degradation
lonized Ca<sup>2+</sup> binding adapter protein 1
Orai1/CRAC
SK3
STIM1
Online Access:http://www.jneuroinflammation.com/content/9/1/250

Internet

http://www.jneuroinflammation.com/content/9/1/250

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