Renal protective effect of polysulfide in cisplatin-induced nephrotoxicity

Renal protective effect of polysulfide in cisplatin-induced nephrotoxicity

Cisplatin is a major chemotherapeutic drug for solid tumors whereas it may lead to severe nephrotoxicity. Despite decades of efforts, effective therapies remain largely lacking for this disease. In the current research, we investigated the therapeutic effect of hydrogen polysulfide, a novel hydrogen...

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Bibliographic Details
Main Authors: Xu Cao, Xiaowei Nie, Siping Xiong, Lei Cao, Zhiyuan Wu, Philip K. Moore, Jin-Song Bian
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Redox Biology
Subjects:
Polysulfide
Hydrogen sulfide
Cisplatin nephrotoxicity
Reactive oxygen species
NADPH oxidase
Nuclear factor erythroid 2-related factor 2
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717308297

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http://www.sciencedirect.com/science/article/pii/S2213231717308297

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