The MicroRNA Landscape of MYCN-Amplified Neuroblastoma

The MicroRNA Landscape of MYCN-Amplified Neuroblastoma

MYCN gene amplification and upregulated expression are major hallmarks in the progression of high-risk neuroblastoma. MYCN expression and function in modulating gene synthesis in neuroblastoma is controlled at virtually every level, including poorly understood regulation at the post-transcriptional...

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Bibliographic Details
Main Authors: Danny Misiak, Sven Hagemann, Jessica L. Bell, Bianca Busch, Marcell Lederer, Nadine Bley, Johannes H. Schulte, Stefan Hüttelmaier
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
microRNAs
MYCN
IGF2BP1
mir-17-92 cluster
diagnostic marker
neuroblastoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.647737/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.647737/full

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