Transcriptional Dysregulation of Upstream Signaling of IFN Pathway in Chronic HCV Type 4 Induced Liver Fibrosis.

IFN orchestrates the expression of various genes to halt hepatitis C virus (HCV) replication with the possibility of either reduced or increased liver fibrosis; due to controlled viral replication or overproduction of inflammatory mediators, repectively. In this study, we examined the transcriptiona...

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Bibliographic Details
Main Authors: Marwa K Ibrahim, Ghada Maher Salum, Noha G Bader El Din, Reham M Dawood, Ahmed Barakat, Ahmed Khairy, Mostafa K El Awady
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4852926?pdf=render