Evaluation of sesamol-induced histopathological, biochemical, haematological and genomic alteration after acute oral toxicity in female C57BL/6 mice

The objective of this study was to evaluate organ-wise toxicological effects of sesamol and determine the LD50 cut-off value and GHS category following acute oral toxicity method OECD 423. An acute oral toxicity study was carried out in female C57BL/6 mice. Observations for physical behaviour and me...

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Bibliographic Details
Main Authors: Shahanshah Khan, Sandeep Choudhary, Arun Kumar, Akanchha Mani Tripathi, Amit Alok, Jawahar Singh Adhikari, Moshahid Alam Rizvi, Nabo Kumar Chaudhury
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Toxicology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750016300257