Hypoxia Mimetic Agents for Ischemic Stroke

Every year stroke claims more than 6 million lives worldwide. The majority of them are ischemic stroke. Small molecule-based therapeutics for ischemic stroke has attracted a lot of attention, but none has been shown to be clinically useful so far. Hypoxia-inducible factor-1 (HIF-1) plays a crucial r...

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Bibliographic Details
Main Authors: Charles K. Davis, Saurabh A. Jain, Ok-Nam Bae, Arshad Majid, G. K. Rajanikant
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00175/full