Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective Study

Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective Study

This retrospective study evaluates the link between an adverse drug reaction (ADR) or a non-response to treatment and cytochromes P450 (CYP), P-glycoprotein (P-gp) or catechol-O-methyltransferase (COMT) activity in patients taking analgesic drugs for chronic pain. Patients referred to a pain center...

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Bibliographic Details
Main Authors: Victoria Rollason, Célia Lloret-Linares, Kuntheavy Ing Lorenzini, Youssef Daali, Marianne Gex-Fabry, Valérie Piguet, Marie Besson, Caroline Samer, Jules Desmeules
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Journal of Personalized Medicine
Subjects:
personalised medicine
cytochrome P450
P-glycoprotein
COMT
analgesic drugs
adverse drug reaction
Online Access:https://www.mdpi.com/2075-4426/10/4/198

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https://www.mdpi.com/2075-4426/10/4/198

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