TLX controls angiogenesis through interaction with the von Hippel-Lindau protein

TLX controls angiogenesis through interaction with the von Hippel-Lindau protein

Summary TLX is known as the orphan nuclear receptor indispensable for maintaining neural stem cells in adult neurogenesis. We report here that neuroblastoma cell lines express high levels of TLX, which further increase in hypoxia to enhance the angiogenic capacity of these cells. The proangiogenetic...

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Bibliographic Details
Main Authors: Zhao-jun Zeng, Erik Johansson, Amiko Hayashi, Pavithra L. Chavali, Nina Akrap, Takeshi Yoshida, Kimitoshi Kohno, Hiroto Izumi, Keiko Funa
Format: Article
Language:English
Published: The Company of Biologists 2012-04-01
Series:Biology Open
Subjects:
TLX
VHL
HIF-2α
Angiogenesis
Neuroblastoma
Online Access:http://bio.biologists.org/content/1/6/527

Internet

http://bio.biologists.org/content/1/6/527

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