Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin

Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin

The calcium-binding protein S100A4 has been described to promote pathological inflammation in experimental autoimmune and inflammatory disorders and in allergy and to contribute to antigen presentation and antibody response after parenteral immunization with an alum-adjuvanted antigen. In this study...

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Bibliographic Details
Main Authors: Jia-Bin Sun, Jan Holmgren, Maximilian Larena, Manuela Terrinoni, Yu Fang, Anne R. Bresnick, Zou Xiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
adjuvant
cholera toxin
dendritic cells
germinal center
S100A4
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01119/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01119/full

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