Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

Abstract Background Noninvasive prenatal testing (NIPT) based on cell-free DNA in maternal circulation has been accepted worldwide by the clinical community since 2011 but limitations, such as maternal malignancy and fetoplacental mosaicism, preclude its full replacement of invasive prenatal diagnos...

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Bibliographic Details
Main Authors: Chung-Er Huang, Gwo-Chin Ma, Hei-Jen Jou, Wen-Hsiang Lin, Dong-Jay Lee, Yi-Shing Lin, Norman A. Ginsberg, Hsin-Fu Chen, Frank Mau-Chung Chang, Ming Chen
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Molecular Cytogenetics
Subjects:
cbNIPD
Aneuploidy
fnRBC
EVT
NIPT
Fish
Online Access:http://link.springer.com/article/10.1186/s13039-017-0343-3

Internet

http://link.springer.com/article/10.1186/s13039-017-0343-3

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