Changes in the transcriptional activity of the entero-insular axis genes in streptozotocin-induced diabetes and after the administration of TNF-α non-selective blockers

Objective. The aim of the present study was to investigate the transcriptional activity of the GLP-1R, DPP-4, SGLT-1, INSR, and IGF-1R genes in GALT cells of rats with streptozotocin-induced diabetes in both untreated and treated with pentoxifylline, as a non-specific blocker of TNF-α.

Bibliographic Details
Main Authors: Degen Anna S., Krynytska Inna Y., Kamyshnyi Aleksandr M.
Format: Article
Language:English
Published: Sciendo 2020-07-01
Series:Endocrine Regulations
Subjects:
Online Access:https://doi.org/10.2478/enr-2020-0019