A copy number variant at the KITLG locus likely confers risk for canine squamous cell carcinoma of the digit.

The domestic dog is a robust model for studying the genetics of complex disease susceptibility. The strategies used to develop and propagate modern breeds have resulted in an elevated risk for specific diseases in particular breeds. One example is that of Standard Poodles (STPOs), who have increased...

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Bibliographic Details
Main Authors: Danielle M Karyadi, Eric Karlins, Brennan Decker, Bridgett M vonHoldt, Gretchen Carpintero-Ramirez, Heidi G Parker, Robert K Wayne, Elaine A Ostrander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3610924?pdf=render