Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites

Bromodomain-containing proteins (BDPs) are involved in the regulation of eukaryotic gene expression. Compounds that bind and/or inhibit BDPs are of interest as tools to better understand epigenetic regulation, and as possible drug leads for different diseases, including malaria. In this study, we as...

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Bibliographic Details
Main Authors: Ming Jang Chua, Dina Robaa, Tina S. Skinner-Adams, Wolfgang Sippl, Katherine T. Andrews
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320718300095